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Top 10 science stories of 2015
Real Clear Science brings us their top 10 science stories of 2015.
1. New Horizons Reaches Pluto
2. Gene Editing Takes Center Stage
3. A New Species of Human: Homo naledi
4. Quantum Entanglement Confirmed
5. A Climate Change Deal Is Struck
6. Salty Water Spotted on Mars
7. Science's Lack of Replication
8. Processed Meat and Red Meat Linked to Cancer
9. A Massive Earthquake in Nepal
10. ISIS Wages War on Archaeology
ΜOΛΩΝ ΛΑΒΕ
Senior Member
Originally Posted by Peter1469
2. Gene Editing Takes Center Stage (48.5 points)Thanks to a revolutionary technique called CRISPR, which was actually developed three years ago, gene editing was a major topic of discussion in 2015. CRISPR may allow scientists to effectively edit genetic diseases out of humanity. It could also potentially be used to engineer humans, themselves.
If this is true, we could do nearly anything to people. the best way to approach this is with indemnity forms for people allowing this upon themselves, as, their bodies will change after they are applied, no telling how long this will take.
Of course, coming up with a theorem for a 'child' and editing the egg cells information will lead to a 'guess' of how the child will grow. think, now, if you were to just try to do something, it might cause suffering, yes?
This means, we could test it on 'older' people, and then watch their bodies slowly change, with their consent. if we want to make people taller, we could observe the differences between short and tall people, and find 'patterns,' yes? i mean, if chromosome 840 is more developed in taller people, on average, then there should be a 'link,' yes? this means we could apply this 'thing' to their bodies via injection, straight into their blood, in various amounts, and the bodies will change, as, they can still grow. maybe reversing it would be possible too?
Now, to make people stop having diseases is a stupid idea for this sort of 'thing.' what diseases are they going to make them immune to? it would take a hell of a long time to make them immune to just one disease - if they want to make them more immune, they should just make lots of white blood cells in their systems. new diseases come out all the time, and, in various forms, so they would be 'upgrading' the system to cope with certain diseases, while the diseases are mutating at a faster rate, so, this is useless. everyone wants to shout out loud that they have cured a disease, and, get lots of money for it.
A much better application would be to make people have thicker yet more detailed nervous systems. this will make the scientists able to handle more complex theorems and stuff. this could be done by taking all the chromosomes in humans and chimps or something, and finding where they vary the most. this would lead to us finding out where the differences are, and, we will be able to work out the next step in evolution, naturally, as we can make a sharper difference where the differences are, and, maybe even have some fun with it!
!! Thug LIfe !!
Peter1469 (12-25-2015)
Senior Member
Quite a breakthrough...
DNA 'tape recorder' to trace cell history
Fri, 27 May 2016 - Researchers invent a DNA "tape recorder" that can trace the family history of every cell in a body.
Researchers have invented a DNA "tape recorder" that can trace the family history of every cell in an organism. The technique is being hailed as a breakthrough in understanding how the trillions of complex cells in a body are descended from a single egg. "It has the potential to provide profound insights into how normal, diseased or damaged tissues are constructed and maintained," one UK biologist told the BBC. The work appears in Science journal. The human body has around 40 trillion cells, each with a highly specialised function. Yet each can trace its history back to the same starting point - a fertilised egg.
Developmental biology is the business of unravelling how the genetic code unfolds at each cycle of cell division, how the body plan develops, and how tissues become specialised. But much of what it has revealed has depended on inference rather than a complete cell-by-cell history. "I actually started working on this problem as a graduate student in 2000," confessed Jay Shendure, lead researcher on the new scientific paper. "Could we find a way to record these relationships between cells in some compact form we could later read out in adult organisms?"
Zebrafish
Overcoming failure
The project failed then because there was no mechanism to record events in a cell's history. That changed with recent developments in so called CRISPR gene editing, a technique that allows researchers to make much more precise alterations to the DNA in living organisms. The molecular tape recorder developed by Prof Shendure's team at the University of Washington in Seattle, US, is a length of DNA inserted into the genome that contains a series of edit points which can be changed throughout an organism's life. Each edit records a permanent mark on the tape that is inherited by all of a cell's descendants. By examining the number and pattern of all these marks in an adult cell, the team can work back to find its origins.
Developmental biologist James Briscoe of the Crick Institute, in London, UK, calls it "a creative and exciting use" of the CRISPR technique. "It uniquely and indelibly marks cells with a 'barcode' that is inherited in the DNA. This means you can use the barcode to trace all the progeny of barcoded cells," he said. Jay Shendure collaborated with molecular biologist Alex Schier of Harvard University to prove the technique on a classic lab organism - the zebrafish. Not only did they show the technique works, they could trace the lineage of hundreds of thousands of cells in mature fish. They also showed it has the power to change perceptions about biological development.
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Peter1469 (05-27-2016)
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