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Thread: Hepatitis research, treatments, updates

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    waltky's Avatar Senior Member
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    Exclamation Hepatitis research, treatments, updates

    Hep C drug may trigger Hep B... Drug for one hepatitis type may activate another: watchdog December 2, 2016 - Drugs against one type of hepatitis may activate another, sometimes with fatal consequences, Europe's medicines watchdog warned on Friday.
    The medicines, which are highly effective against hepatitis C, may trigger latent hepatitis B in patients infected with both types, the European Medicines Agency said in a statement. It named the antivirals Daklinza, Exviera, Harvoni, Olysio, Sovaldi and Viekirax used to treat chronic hepatitis C, an infectious liver disease. "Cases of the return of previously inactive hepatitis B infection, which can be fatal, have been reported in patients treated," with this class of drug, the agency said in a statement announcing the findings of a probe. There have been only about 30 cases of hepatitis B reactivation out of thousands of patients taking the drugs, the agency said. And there was not enough information to draw a conclusion on cancer risk. But a special risk assessment committee of the agency recommended that all patients be screened for hepatitis B virus before starting any of these treatments. It also proposed that a warning be included in the drug information leaflet. The drugs, a new class known as "direct-acting antivirals" are more effective than their predecessors. At a cost of some 40,000 to 80,000 euros ($43,000-$86,000) for a 12-week course, they are the preserve of a lucky few. Hepatitis is an inflammation of the liver, most often caused by a virus but sometimes by drug or alcohol abuse, other infections, or autoimmune diseases. The B and C types usually occur from contact with body fluids of an infected person. Other than for hepatitis B, there is no vaccine against hepatitis C. https://www.yahoo.com/news/drug-one-...95.html?ref=gs

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    stjames1_53 (12-02-2016)

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    stjames1_53's Avatar Senior Member
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    a friend of mine was on one of those experiments. He had Hep-C and developed liver cancer. Someone, somewhere is alive because of what he went through, then. They have a treatment/recession program that works now.
    It was harsh watching him go through the process.
    For waltky: http://quakes.globalincidentmap.com/
    "The Nation that makes a great distinction between its scholars and its warriors will have its thinking done by cowards and its fighting done by fools."
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    waltky's Avatar Senior Member
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    Angry

    Scopes not properly cleaned...

    Air Force: 135 Patients May Have Been Exposed to HIV, Hepatitis
    20 Jun 2017 | The U.S. Air Force is notifying 135 patients who received colonoscopy or endoscopy procedures at Al Udeid Air Base in Qatar that they may have been exposed to blood-borne diseases such as HIV or hepatitis.
    Air Force Medical Services announced Tuesday that scopes used for the upper and lower gastrointestinal procedures over an eight-year-period from April 2008 and April 2016 at the base clinic were not properly cleaned in accordance with Food and Drug Administration guidelines, Office of the Air Force Surgeon General spokeswoman Larine Barr told Military.com on Wednesday. As a result, patients could have been exposed to possible viral infections that include human immunodeficiency virus, known as HIV, "and two kinds of Hepatitis (B & C)," Barr said. "The risk of infection is very small, particularly in a deployed environment, but we recommend that patients receive diagnostic testing," she said in an email.


    The Air Force review determined that medical technicians used "an alternate method that included manual cleaning and inspection, rather than the recommended automated process," she said. "Specifically, it was noted that during equipment reprocessing, the flushing and brushing of the scope lumens were not completed as recommended by the manufacturer," she said. The service reiterated that analysis by infectious disease experts shows the risk of contracting the diseases is very low, but still encourage additional testing. "Providing quality health care to our Airmen and their families is our top priority," Brig. Gen. Robert Miller, Air Force Medical Operations Agency commander, said in the release. "We apologize to our patients and assure them that appropriate actions have been taken to address and mitigate the causes that led to this problem."



    Air Force doctors perform a diagnostic procedure on a patient.



    The Air Force said it has since taken preventative measures, including a "service-wide patient safety alert" for medical technicians to review and comply with proper endoscope cleaning, decontamination, inspection and sterilization processes. In addition, military treatment facility commanders have also been directed "to complete the same review of all reusable medical instruments and devices" and experts are analyzing "best practices" procedures moving forward to prevent the same issue from occurring, the release said. Officials noted that the Al Udeid clinic no longer performs endoscopy and colonoscopy procedures, and that all other procedures performed at the clinic were unaffected.


    Miller said, "it's important for anyone who receives a notification to contact us to discuss the situation and if they desire to pursue diagnostic testing. Our medical team is here to address concerns and help patients throughout this entire process." The Air Force said patients with questions or concerns may reach out to their healthcare resolution specialist at the following contacts: U.S. Eastern Daylight time zone or outside the continental U.S.: (937) 656-3818; U.S. Pacific or Mountain time zone, Hawaii, or Alaska: (707) 423-3443; and Central time zone: (228) 376-5603.


    http://www.military.com/daily-news/2...hepatitis.html

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    My 64 YO friend took harvoni, not only did it not cure him, it cut his remaining liver function in half
    There is no God but Resister and Refugee is his messenger’.

    Book of Democrat Things, Chapter 1:1






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    waltky (06-22-2017)

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    Exclamation

    Homeless community in L.A. hit by Hep A outbreak...

    California Experiences Hepatitis A Outbreak
    November 24, 2017 — The U.S. state of California is experiencing the largest person-to-person outbreak of hepatitis A in the United States since a vaccine to prevent the liver disease became available in 1996.
    More than 600 cases have been reported in the state and 21 people have died. According to the California Department of Public Health, most of those infected are homeless or use drugs in places where sanitation has been a challenge. “There should be more hand-washing and bathrooms,” said a man who has been homeless for more than four years. Identifying himself only as J-el, he lives on Skid Row, an area in downtown Los Angeles known for its homeless population.


    Far below UN standard


    A recent study conducted by Skid Row advocates, organizations and residents found that the area fell short of U.N. refugee camp standards calling for one public toilet for every 20 people. According to the report, during daytime hours, with a street population of more than 3,600 people, Skid Row is as many as 164 toilets short of the U.N. standard. At night, the Skid Row population drops to about 1,700 people who live on the streets. The city of Los Angeles said there are only six public toilets in the downtown area that are open 24 hours a day.



    A homeless man takes food from a trash can in Los Angeles' Skid Row area, home to the nation's largest concentration of homeless people, Oct. 28, 2017, in Los Angeles. California declared a statewide emergency because of a hepatitis A outbreak linked to homeless encampments. Comparisons are being made to conditions more commonly seen in Third World countries.



    Critics said illicit activities can occur, which is a reason why some public bathrooms are not open at night. “They (the city) don’t want to let you use the toilet so it’s a problem here, and it’s somewhat of a problem with us (homeless people) as people (be)cause we mess up the toilet some of us, mess up the toilet, and then ... but at the same time, the people who don’t, they get penalized and can’t use it. They got to end up using it out here some place,” said J-el referring to the side of the street as a place where many people who are homeless use as bathrooms.



    Lying on a urine-stained sidewalk, two homeless drug addicts hallucinate in Los Angeles' Skid Row area, home to the nation's largest concentration of homeless people


    Unsanitary conditions can become a breeding ground for the hepatitis A virus, said Jeff Klausner, professor of medicine and public health at the University of California, Los Angeles. “Right now the outbreaks in San Diego and Los Angeles of hepatitis A is being spread by poor sanitation, person-to-person spread, and contaminated, unclean feces or inability for people to wash their hands,” Klausner said.


    Enter Lava Mae
    See also:

    California Declares Emergency to Fight Hepatitis A Outbreak
    October 13, 2017 — California Gov. Jerry Brown on Friday declared a state of emergency to combat a hepatitis A outbreak that has claimed 18 lives in San Diego.
    Brown said the federally funded supply of vaccines is inadequate. His proclamation allows the state to buy vaccines directly from manufacturers and distribute them. The declaration “allows us to move very swiftly,” Dr. Gil Chavez, epidemiologist at the California Department of Public Health, told reporters. He said the state would place an order Monday or Tuesday and supplies would reach the state soon after. California has distributed 81,000 federally funded vaccine doses since the outbreak began and local jurisdictions have acquired more, but the supply is insufficient, Chavez said.

    Largest outbreak since 1996

    California is experiencing the largest hepatitis A outbreak in the United States transmitted from person to person, instead of by contaminated food, since the vaccine became available in 1996. The state says most of those affected are homeless, using drugs or both. There have been 576 cases throughout California, including 490 in San Diego County, 71 in Santa Cruz County and eight in Los Angeles County. Out of those, 386 people have been hospitalized, including 342 in San Diego, 33 in Santa Cruz and six in Los Angeles. No deaths have been reported outside San Diego County.

    U.S. Rep. Darrell Issa on Friday called on the federal government to provide emergency funding to halt the spread of hepatitis A. He said the outbreak has brought statewide totals to three times the number of reported cases in 2015. “We cannot wait until more communities are infected and impacted before taking action,” the San Diego-area Republican wrote to the U.S. Health and Human Services Department and the Centers for Disease Control and Prevention. A message seeking comment from the Centers for Disease Control and Prevention wasn’t immediately returned.

    Outbreak began in March

    San Diego County reported an outbreak in March as it grapples with a growing homeless population. Santa Cruz County reported its first cases the following month, and San Diego and Los Angeles counties declared local health emergencies in September. The outbreak was caused by strains of the 1B genetic subtype, which is rare in the United States and more commonly found in the Mediterranean and South Africa. It is spread through contact with feces, putting people with inadequate access to sanitation at highest risk. In addition to vaccination, frequent handwashing is recommended.

    https://www.voanews.com/a/california...k/4069804.html
    Last edited by waltky; 11-24-2017 at 05:51 PM.

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    Kacper (11-24-2017)

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    With all the needle users among the under 30 crowd in my area, the faster they find a better treatment for Hep the better

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    waltky (11-25-2017)

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