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Thread: Ulcerative colitis & other Inflammatory Bowel Disorders

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    waltky's Avatar Senior Member
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    Question Ulcerative colitis & other Inflammatory Bowel Disorders

    Who wants to eat monkey worms? Yuch!...

    Parasitic worms 'treat diarrhoea'
    15 November 2012 - Chronic diarrhoea could be treated using parasitic worms, a study of monkeys has suggested.
    Research published in PLOS Pathogens, suggests the treatment restores gut bacteria to a healthy state. Other work in mice has already suggested conditions such as ulcerative colitis could be treated in this way. A UK expert said parasitic worms were being investigated for a range of conditions, including multiple sclerosis and allergies.

    Captivity

    Inflammatory bowel diseases, like colitis, are often fuelled by a wrongly targeted response by the immune system to gut bacteria. Such diseases are more common in developed countries - and scientists suggest this is because people in developing countries have more exposure to parasitic worm (helminth) infections and therefore have a natural protection that has evolved as people and worms learnt to co-exist.


    Macaque monkeys suffer from a similar bowel condition to humans

    Recent studies have used parasitic worms to successfully treat inflammatory bowel disease in humans, but it is unclear exactly how they do this. This latest study looked at monkeys because young macaques kept in captivity often develop chronic diarrhoea that can be hard to treat. Five macaques with diarrhoea were treated with parasitic worms called whipworms.

    Tissue samples were taken before and after treatment and it was found the balance of gut bacteria was restored to required levels. And four out of five animals had less diarrhoea and started to gain weight. Dr P'ng Loke, of the New York University Langone Medical Center, who led the study, said: "The idea for treating colitis with worms is not new, but how this therapy might work remains unclear.

    More http://www.bbc.co.uk/news/health-20341418

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    roadmaster (11-15-2012)

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    WALT....I SWEAR!! YOU are just the LIFE of the PARTY!!

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    I don't think I would want to. Remember when they use to use maggots and leeches to treat things?
    It seems to be coming back.

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    It'll be the only thing we can afford.

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    Quote Originally Posted by Calypso Jones View Post
    WALT....I SWEAR!! YOU are just the LIFE of the PARTY!!
    Don't make him feed you a monkey worm.

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    Let's NOT encourage him. Where is he getting this stuff!

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    Stent 'may help bowel cancer treatment'...

    Bowel cancer: Stents 'may prevent need for colostomy bags'
    Sun, 05 Jun 2016 - A expandable tube, or stent, inserted into the bowels of cancer patients can cut the odds of them needing a colostomy bag, cancer doctors say.
    Bowel cancer patients may avoid the need for colostomy bags if they are first treated by having an expandable tube inserted at the site of their blockage, cancer doctors have said. The new approach, presented at the world's biggest cancer conference, showed that the tube, or stent, cut the risk of complications from surgery. Experts said colostomy bags, to collect faeces, often frightened patients. Globally, nearly 1.4 million cases of bowel cancer are diagnosed each year.

    In the UK, more than a fifth of the cancers go undetected until the tumour blocks the intestines, leaving patients needing emergency surgery. This unplanned surgery has a much higher risk of complications compared with routine surgery. The patient is often in worse health, the swelling caused by the blockage can mean keyhole surgery is not possible so more invasive surgery is needed and there may not be a colorectal specialist surgeon on hand. The death rate goes up from 2% for planned surgery to 12% in emergency bowel cancer surgery.


    Distended

    After removing the tumour and surrounding bowel, surgeons are also less likely to be able to re-plumb the bowels. One part of the colon is often hugely distended and the other collapsing in on itself. If it cannot be put back together properly, the risk of needing a colostomy bag soars. A trial on 250 patients was organised by Cancer Research UK. Half were treated with conventional surgery, but the others had a novel procedure to unblock the bowels. Surgeons used an endoscope to find the precise location of the blockage and then positioned a stent at the site of obstruction. When inserted, the tube is just 3mm in diameter. But over 48 hours it expands in response to body heat until it reaches 2.5cm in diameter, creating a new clear passageway through the intestines.

    The tumour is then removed once the bowels have healed and the patient has recovered from the blockage. There was no difference in survival rates between the procedures, but the difference in the need for a colostomy bag was stark. In the emergency patients, 69% needed a bag to rid their bodies of faeces. In those treated with the stent, the figure was 45%, according to data presented at the American Society of Clinical Oncology's annual meeting in Chicago.

    'Huge improvement'

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    Younger, Middle-aged adults experiencing rise in colon cancer...

    Colorectal Cancer Rising Among Younger Adults
    February 28, 2017 - Americans born in 1990 have double the risk of colon cancer and quadruple the risk of rectal cancer than those born around 1950, a new study suggests.
    The study found that colorectal cancer is on the rise among young and middle-aged adults in their early 50s. Rectal cancer is growing particularly fast among people younger than 55, with 30 percent of diagnoses in people under 55. "Trends in young people are a bellwether for the future disease burden," said Rebecca Siegel, of the American Cancer Society and lead author of the study that appeared in the Journal of the National Cancer Institute. "Our finding that colorectal cancer risk for millennials has escalated back to the level of those born in the late 1800s is very sobering. Educational campaigns are needed to alert clinicians and the general public about this increase to help reduce delays in diagnosis, which are so prevalent in young people, but also to encourage healthier eating and more active lifestyles to try to reverse this trend."

    Researchers note that rates of colorectal cancer have been falling since the 1980s with an even steeper decline in the past decade, which has been caused by more screening. But they wanted to find out why some studies have shown a rising rate among people under 50 for whom screening is generally not done. For their study, researchers looked at cases of colorectal cancer in people over 20 from 1974 to 2013. There were 490,305 cases.


    Colon cancer is one of the world's deadliest diseases, but it often has no symptoms in the early stages. That's why doctors urge adults over 50 to have a colonoscopy to detect any possible cancer.

    The data showed the rates of colon cancer initially decreased after 1974, but then grew by one or two percent from the mid-1980s to 2013 among adults aged 20 to 39. For people aged 40 to 54, the rates increased between .5 percent and one percent from the mid 1990s to 2013. For rectal cancer, the increases were greater, with rates rising about three percent per year from 1974 to 2013 in adults aged 20 to 29. For adults between 30 and 39, there was a similar rise from 1980 to 2013. For adults between 40 and 54, rates increased by two percent from the 1990s to 2013.

    Rates for adults older than 55 has been declining for about 40 years, researchers said. Researchers say the results could change the age at which screening for colorectal cancer starts and cite 10,400 cases diagnosed in people in their 40s plus 12,800 cases in people in their early 50s. "These numbers are similar to the total number of cervical cancers diagnosed, for which we recommend screening for the 95 million women ages 21 to 65 years," Siegel said.

    http://www.voanews.com/a/mht-colorec...s/3743648.html
    See also:

    Study: Heroin Overdose Deaths Quadruple Between 2010-2015
    February 24, 2017 - Deaths caused by heroin overdoses in the United States quadrupled between 2010 and 2015, according to a new report.
    The National Center for Health Statistics says there were 12,989 overdose deaths involving heroin in 2015. In 2010, the number was 3,036. In percentages, heroin caused 8 percent of drug overdose deaths in 2010, and now it accounts for 25 percent. The center cites dropping prices and increasing potency for the rise in deaths.


    A man injects himself with heroin using a needle obtained from the People's Harm Reduction Alliance, the nation's largest needle-exchange program, in Seattle, Washington.

    Furthermore, experts say they believe the opioid epidemic caused by prescription painkillers may also be driving people to use heroin as the drug is usually much cheaper. "You are 40 times more likely to use heroin if you started with opioid painkillers," Rich Hamburg, the executive vice president for the non-profit Trust for America’s Health, told the Reuters news agency. "Heroin is part of America's larger drug abuse problem."

    Death from overdosing on prescription painkillers like oxycodone actually fell over the period of the study, dropping from 29 percent of all overdose deaths in 2010 to 24 percent in 2015. Overdoses deaths from cocaine also fell, albeit slightly, the study said. The states with the highest rates of overdose deaths in 2015 were West Virginia, New Hampshire, Kentucky and Ohio, the study found. Overdose deaths increased for all age groups, but rose the most among those 55 to 64, the study said.

    http://www.voanews.com/a/mht-heroin-...e/3738509.html

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    Colorectal cancer chances could be reduced with a combination of diet and exercise. Heredity probably plays a role, but the American diet of fast food, processed foods, GMOs, etc. are the number one culprit.

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    waltky (03-01-2017)

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    Bowel cancer tests 'failing' in the UK...

    Hospitals 'failing' on genetic bowel cancer test
    27 March 2018 - More than 80% of NHS hospitals in England are failing to test bowel cancer patients for the genetic condition Lynch syndrome, according to the charity Bowel Cancer UK.
    The condition increases the risk of bowel and other cancers. Bowel Cancer UK estimates that 166,000 people in the UK are unaware that they have the condition. An NHS England spokeswoman said there are clear guidelines about when it is appropriate to test for Lynch syndrome. Testing for the syndrome can guide the treatment of the patient and indicates whether their families are at risk. Children of people with the condition have a 50/50 chance of developing it.


    The charity says it is important to find out whether patients have Lynch syndrome, because some chemotherapy drugs are ineffective for them. And if other family members find they have the syndrome then it enables them to take steps to reduce their risk of bowel cancer, or be diagnosed at an earlier stage when it is easier to treat. Teenage cancer fundraiser Stephen Sutton, who died of bowel cancer at 19, had Lynch syndrome. His father had twice battled bowel cancer. When Stephen presented with similar symptoms he was told he was too young to get the disease, delaying his diagnosis for six months.


    The National Institute for Health and Care Excellence (NICE) guidelines recommend testing all bowel cancer patients for Lynch syndrome at the time of their diagnosis. A Freedom of Information request by the charity found that 83% of NHS hospitals in England are not testing for the condition. They said that 91% of those hospitals cited financial reasons as the main barrier and 61% said staff resources were a problem. One hospital trust said: "The main barriers have been, and remain, financial and staff resources. NICE produce guidance but the government do not provide the funding for the implementation of the guidance. It is a recurring theme and, with the increasing use of genomic medicine, is a major problem for pathology departments."


    But the charity says the cost of the test is small compared to the cost of treating patients for bowel cancer, which they say is around £25,000. Deborah Alsina, chief executive of Bowel Cancer UK and Beating Bowel Cancer, said: "The price of testing for Lynch syndrome is peanuts - only £200 per patient. Clinical Commissioning Groups (CCGs) need to loosen the purse strings as the price of testing for Lynch syndrome far outweighs the cost of treating bowel cancer patients. "A lack of funding and resources from CCGs means that hospitals' hands are tied. Until these issues are being addressed, generations of families will continue to be devastated by cancer and lives will be needlessly lost."


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