How hot peppers and marijuana could help cure gut problems...
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Unlike the rest of the body, which tends to treat foreign invaders with a singular purpose—seek and destroy—the stomach cannot afford to be so indiscriminate. It exists to help fuel the body, and that means routinely welcoming foreign bodies in the form food. If physically hot temperatures activate the immune cells, Srivastava wondered, would capsaicin—the chemical that makes chili peppers feel hot—do the same? The answer was yes. Immune cells exposed to chili pepper in a Petri dish behaved just like cells exposed to higher temperatures.
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In the meantime? Well, if you live in Colorado and want to try something new for your IBD, you’re sure in luck. But most patients should probably hold off on trying to mimic the study results at home: many IBD patients report negative reactions to spicy foods, likely because they increase stomach acid and often contain nightshade plants. So guzzling hot sauce might not be a safe way to boost your body’s anandamide production.
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https://www.popsci.com/peppers-marijuana-gut/