— And separate cohort found high risk with COVID infection
The Pfizer COVID-19 mRNA vaccine was found to be associated with a threefold increased risk of myocarditis, according to a real-world case-control study from Israel.
Vaccination had a strong association with an increased risk of myocarditis (risk ratio [RR] 3.24, 95% CI 1.55-12.44, risk difference 2.7 events per 100,000 persons), as well as increased risks of lymphadenopathy (RR 2.43, 95% CI 2.05-2.78, 78.4 per 100,000), appendicitis (RR 1.40, 95% CI 1.02-2.01, 5.0 per 100,000), and herpes zoster infection (RR 1.43, 95% CI 1.20-1.73, 15.8 per 100,000), reported Ran Balicer, MD, of Clalit Health Services in Tel Aviv, and colleagues.
However, in a separate cohort, infection with SARS-CoV-2 was associated with a higher risk of myocarditis (RR 18.28, 95% CI 3.95-25.12, 11.0 per 100,000), as well as other cardiovascular complications, including acute kidney injury (RR 14.83, 95% CI 9.24-28.75, 125.4 per 100,000), pulmonary embolism (RR 12.14, 95% CI 6.89-29.20, 61.7 per 100,000), and intracranial hemorrhage (RR 6.89, 95% CI 1.90-19.16, 7.6 per 100,000), the authors wrote in the New England Journal of Medicine.
They noted that vaccination was "substantially protective" against anemia, acute kidney injury, intracranial hemorrhage, and lymphopenia.
Participants in the vaccination cohorts were 16 years old and older, had been in the health organization for a full year, had no prior COVID-19 infection, and had no contact with the healthcare system in the last 7 days.
Overall, 884,828 people each were included in the vaccination cohort and the unvaccinated cohort, though 235,541 in the unvaccinated cohort had to be rematched following vaccination. The researchers also included 173,106 people with COVID-19 infection matched with the same number of uninfected people......snip~
Real-World Study Captures Risk of Myocarditis With Pfizer Vax | MedPage Today
Looks like there is more of a problem with the Pfizer Vaccine than the CDC was letting on. But hey says JoeyB get the vaccine!